AT-406 HCl ( —— )

产品货号. M17137 CAS No. 1071992-57-8

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产品名称

AT-406 HCl
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

AT-406, an orally active antagonist of multiple inhibitor of apoptosis proteins(IAP).
产品描述

AT-406, an orally active antagonist of multiple inhibitor of apoptosis proteins(IAP), inhibits progression of human ovarian Y binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide.
同义词

——
通路

Others
靶点

Other Targets
受体

Apoptosis protein
研究领域

——
适应症

——

CAS Number

1071992-57-8
分子量

598.19
分子式

C32H44ClN5O4
纯度

98%
溶解度

——
SMILES

N12[C@@H](CCN(C[C@@H](C1=O)NC(=O)[C@H](C)NC)C(=O)CC(C)C)CC[C@H]2C(=O)NC(c1ccccc1)c1ccccc1
化学全称

——

1. Melissa KB, et al. Y Biol Ther. 2012 Jul 1; 13(9): 804–811.

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